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Andrew David Foote

Associate Professor - Sex and Evolution Research Group
Image of Andrew David Foote
Username
Visiting address Sars gate 1 0562 Oslo
Postal address Postboks 1172, Blindern 0318 Oslo

Academic interests

I am an evolutionary biologist using ancient and modern DNA to study evolution through space and time. My research asks how populations adapt to new environments, how demographic history shapes genetic diversity, and what genomic time series can reveal about the tempo and predictability of evolutionary change.

Much of my work focuses on two study systems. In threespine stickleback, I use subfossil bones and sedimentary ancient DNA from Norwegian isolation basins to observe freshwater adaptation as it unfolded at the end of the last glacial period. This lets me track when, and in what order, adaptive alleles rose in frequency. I also study how founder effects and regions of low recombination, such as chromosomal inversions, constrain or facilitate adaptation. In killer whales, I combine contemporary and ancient genomes to reconstruct population history and the post-glacial colonisation of high-latitude waters. I also examine the genetic consequences of small population size, including inbreeding, mutation load and purging. Across both systems, and in bottlenose dolphins, I am interested in how selection on ancestral standing variation drives the repeated formation of ecotypes.

As a member of the Sex and Evolution Research Group, I also work on the genetics of sex-specific traits, such as the evolution of menopause in killer whales, the role of the X chromosome, and sex differences in recombination.

Museum collections are central to my research. Specimens provide a temporal record of past genetic variation, so we can directly compare populations before, during and after evolutionary change. My work also contributes genomic resources for cetacean research and conservation, through reference genomes and population genomic studies of threatened killer whale populations. Beyond genomics, I am interested in the social lives of whales and dolphins, and I co-edited 'The Evolution of Cetacean Societies' (University of Chicago Press, 2026).

Background

I completed a BSc (Hons) in 'Science and the Environment' at De Montfort University in 1994. I returned to research with a part-time Masters by research at the University of Durham (2002–2005), studying killer whale vocal behaviour, and then a PhD at the University of Aberdeen (2006–2010) on the evolutionary ecology of North Atlantic killer whales.
My postdoctoral career took me across Europe. I held a Marie Curie Fellowship at the University of Copenhagen (2011–2013), where I began working with ancient DNA, followed by a Lawski Foundation Fellowship at Uppsala University (2013–2015) and a position as visiting researcher and lecturer at the University of Bern (2015–2016). I returned to the UK on a second Marie Curie Fellowship at Bangor University (2016–2019). I then moved to Norway as Associate Professor at NTNU, Trondheim (2020–2023), and as a Researcher at the Centre for Ecological and Evolutionary Synthesis (CEES) University of Oslo (2023–2026), before joining the Natural History Museum, Oslo as Associate Professor in 2026.
My research has been funded by an ERC Consolidator Grant, a Research Council of Norway FRIPRO grant, the Peder Sather Program and two Marie Curie Fellowships. I have supervised or co-supervised PhD students at institutions in Europe, Australia and North America. I teach research-led courses in population genetics, ancient DNA and marine mammal genomics, including an intensive practical course on population genetics with ancient DNA data.

 

Tags: evolutionary genomics, ancient DNA, sedimentary aDNA, population genomics, adaptation, killer whales, threespine stickleback, cetaceans, museomics

Publications

  • Nickel, Jana Helene; Laine, Jan Tapio & Foote, Andrew David (2026). Complex Patterns of Hitchhiking Mutation Load Among Stickleback Populations. Genome Biology and Evolution (GBE). 18(4). doi: 10.1093/gbe/evag088. Full text in Research Archive
  • Foote, Andrew David & Croft, Darren Paul (2025). Sexually antagonistic selection, X-chromosome relatedness and the evolution of menopause in killer whales. Biology Letters. ISSN 1744-9561. 21(12). doi: 10.1098/rsbl.2025.0528. Full text in Research Archive
  • A., Morin, Phillip; Bernhard, Bein,; Chiara, Bortoluzzi,; V., Bukhman, Yury; Taylor, Hains, & Dorothea, Heimeier, [Show all 53 contributors for this article] (2025). Genomic infrastructure for cetacean research and conservation: reference genomes for eight families spanning the cetacean tree of life. Frontiers in Marine Science. 12, p. 1–24. doi: 10.3389/fmars.2025.1562045. Full text in Research Archive
  • Laine, Jan Tapio; Nickel, Jana Helene; Romundset, Anders & Foote, Andrew David (2025). Ancient stickleback genomes reveal the early stages of parallel adaptation. Evolution. ISSN 0014-3820. 79(11), p. 2446–2459. doi: 10.1093/evolut/qpaf164. Full text in Research Archive
  • Foote, Andrew David; Gilbert, Marcus Thomas Pius; Shyam, Gopalakrishnan,; Marie, Louis,; Martin, Michael David & A., Morin, Phillip [Show all 9 contributors for this article] (2025). Evidence of long-term purging of mutation burden in killer whale Orcinus orca genomes. Heredity. ISSN 0018-067X. 134, p. 671–679. doi: 10.1038/s41437-025-00806-5. Full text in Research Archive
  • Filatova, Olga A.; Fedutin, Ivan D.; Borisova, Ekaterina A.; Meschersky, Ilya G.; Shitova, Marina V. & Hoyt, Erich [Show all 7 contributors for this article] (2025). Complete Mitochondrial Genomes Provide Evidence of a Killer Whale Refugium Off the Coast of Japan During the Last Glacial Maximum. Journal of Biogeography. ISSN 0305-0270. 52(8). doi: 10.1111/jbi.15159. Full text in Research Archive
  • Baumgartner, Chérine D.; Jourdain, Eve Marie; Bonhoeffer, Sebastian; Borgå, Katrine; Heide-Jørgensen, Mads P. & Karoliussen, Richard [Show all 13 contributors for this article] (2025). Kinship clustering within an ecologically diverse killer whale metapopulation. Heredity. ISSN 0018-067X. 134, p. 109–119. doi: 10.1038/s41437-024-00740-y. Full text in Research Archive
  • Reeves, Isabella M.; Totterdell, John A.; Sandoval-Castillo, Jonathan; Betty, Emma L.; Stockin, Karen A. & Stewart, Ramari Oliphant [Show all 8 contributors for this article] (2025). Admixture Increases Genetic Diversity and Adaptive Potential in Australasian Killer Whales. Molecular Ecology. ISSN 0962-1083. 34(23). doi: 10.1111/mec.17689. Full text in Research Archive
  • Laine, Jan Tapio; Mak, Sarah S.T.; Martins, Nuno F.G.; Chen, Xihan; Gilbert, Marcus Thomas Pius & Jones, Felicity C. [Show all 9 contributors for this article] (2024). Late Pleistocene stickleback environmental genomes reveal the chronology of freshwater adaptation. Current Biology. ISSN 0960-9822. 34(5), p. 1142–1147. doi: 10.1016/j.cub.2024.01.056. Full text in Research Archive
  • Jourdain, Eve Marie; Karoliussen, Richard; Martin, Sarah Louise; Langangen, Øystein Ole Gahr; Robeck, Todd & Borgå, Katrine [Show all 8 contributors for this article] (2024). Social and genetic connectivity despite ecological variation in a killer whale network. Proceedings of the Royal Society of London. Biological Sciences. ISSN 0962-8452. 291(2021). doi: 10.1098/rspb.2024.0524. Full text in Research Archive
  • Meyer, Laura; Barry, Pierre; Riquet, Florentine; Foote, Andrew David; Der Sarkissian, Clio & Cunha, Regina L. [Show all 13 contributors for this article] (2024). Divergence and gene flow history at two large chromosomal inversions underlying ecotype differentiation in the long-snouted seahorse. Molecular Ecology. ISSN 0962-1083. doi: 10.1111/mec.17277. Full text in Research Archive
  • Garroway, Colin J.; Greef, Evelien de; Lefort, Kyle J.; Thorstensen, Matt J.; Foote, Andrew David & Matthews, Cory J. D. [Show all 13 contributors for this article] (2024). Climate change introduces threatened killer whale populations and conservation challenges to the Arctic. Global Change Biology. ISSN 1354-1013. 30(6). doi: 10.1111/gcb.17352. Full text in Research Archive
  • Foote, Andrew David; Alexander, Alana; Ballance, Lisa T.; Constantine, Rochelle; Muñoz, Bárbara Galletti Vernazzani & Guinet, Christophe [Show all 15 contributors for this article] (2023). "Type D" killer whale genomes reveal long-term small population size and low genetic diversity. Journal of Heredity. ISSN 0022-1503. 114(2), p. 94–109. doi: 10.1093/jhered/esac070. Full text in Research Archive
  • Reeves, Isabella; Totterdell, John A.; Betty, Emma; Donnelly, David M.; George, Angela & Holmes, Steven [Show all 11 contributors for this article] (2023). Ancestry testing of "Old Tom," a killer whale central to mutualistic interactions with human whalers. Journal of Heredity. ISSN 0022-1503. 114(6), p. 598–611. doi: 10.1093/jhered/esad058. Full text in Research Archive
  • Louis, Marie; Korlević, Petra; Nykänen, Milaja; Archer, Frederick; Berrow, Simon & Brownlow, Andrew [Show all 18 contributors for this article] (2023). Ancient dolphin genomes reveal rapid repeated adaptation to coastal waters. Nature Communications. 14(1). doi: 10.1038/s41467-023-39532-z. Full text in Research Archive
  • Louis, Marie; Korlević, Petra; Nykänen, Milaja; Archer, Frederick I.; Berrow, Simon & Brownlow, Andrew [Show all 18 contributors for this article] (2022). Ancient dolphin genomes reveal rapid repeated adaptation to coastal waters. BioRxiv. ISSN 0362-4331. doi: 10.1101/2022.11.03.515020. Full text in Research Archive
  • Foote, Andrew; Bunskoek, Paulien & Sanger, Wellcome (2022). The genome sequence of the killer whale, Orcinus orca (Linnaeus, 1758). Wellcome Open Research. 7. doi: 10.12688/wellcomeopenres.18278.1. Full text in Research Archive
  • Foote, Andrew (2022). Are “Type 2” killer whales long in the tooth? A critical reflection on the discrete categorization of Northeast Atlantic killer whales. Marine mammal science. ISSN 0824-0469. 39, p. 345–350. doi: 10.1111/mms.12964. Full text in Research Archive
  • Kirch, Melanie; Romundset, Anders; Gilbert, Marcus Thomas Pius; Jones, Felicity C. & Foote, Andrew (2021). Ancient and modern stickleback genomes reveal the demographic constraints on adaptation. Current Biology. ISSN 0960-9822. 31, p. 2027–2036. doi: 10.1016/j.cub.2021.02.027. Full text in Research Archive
  • Louis, Marie; Galimberti, Marco; Archer, Frederick; Berrow, Simon; Brownlow, Andrew & Fallon, Ramon [Show all 15 contributors for this article] (2021). Selection on ancestral genetic variation fuels repeated ecotype formation in bottlenose dolphins. Science Advances. 7(44). doi: 10.1126/sciadv.abg1245. Full text in Research Archive
  • Foote, Andrew; Hooper, Rebecca; Alexander, Alana; Baird, Robin; Baker, Charles Scott & Ballance, Lisa [Show all 34 contributors for this article] (2021). Runs of homozygosity in killer whale genomes provide a global record of demographic histories. Molecular Ecology. ISSN 0962-1083. 30(23), p. 6162–6177. doi: 10.1111/mec.16137. Full text in Research Archive
  • Foote, Andrew; Gilbert, Marcus Thomas Pius; Gopalakrishnan, Shyam; Louis, Marie; Martin, Michael David & Morin, Phillip A. [Show all 9 contributors for this article] (2021). Evidence of long-term purging of mutation load in killer whale genomes. BioRxiv. ISSN 0362-4331. doi: 10.1101/2021.08.21.457186. Full text in Research Archive
  • Papadopulos, Alexander; Helmstetter, A.; Osborne, Owen; Comeault, Aaron; Wood, Daniel & Straw, Edward [Show all 13 contributors for this article] (2021). Rapid Parallel Adaptation to Anthropogenic Heavy Metal Pollution. Molecular Biology and Evolution (MBE). ISSN 0737-4038. 38(9), p. 3724–3736. doi: 10.1093/molbev/msab141. Full text in Research Archive
  • Dehasque, Marianne; Ávila-Arcos, María C; Díez-del-Molino, David; Fumagalli, Matteo; Guschanski, Katerina & Lorenzen, Eline D. [Show all 15 contributors for this article] (2020). Inference of natural selection from ancient DNA. Evolution Letters. 4(2), p. 94–108. doi: 10.1002/evl3.165. Full text in Research Archive
  • Morin, Phillip A.; Alexander, Alana; Blaxter, Mark; Caballero, Susana; Fedrigo, Olivier & Fontaine, Michaël C. [Show all 16 contributors for this article] (2020). Building genomic infrastructure: Sequencing platinum-standard reference-quality genomes of all cetacean species. Marine mammal science. ISSN 0824-0469. 36(4), p. 1356–1366. doi: 10.1111/mms.12721. Full text in Research Archive
  • Hosegood, Jane; Humble, Emily; Ogden, Rob; Bruyn, Mark de; Creer, Simon & Stevens, Guy [Show all 25 contributors for this article] (2020). Phylogenomics and species delimitation for effective conservation of manta and devil rays. Molecular Ecology. ISSN 0962-1083. 29(24), p. 4783–4796. doi: 10.1111/mec.15683. Full text in Research Archive

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  • Croft, Darren P.; Foote, Andrew David; Garland, Ellen C. & King, Stephanie L. (2026). The Evolution of Cetacean Societies. University of Chicago Press. ISBN 9780226840574. 436 p. doi: https:/press.uchicago.edu/ucp/books/book/chicago/E/bo257312594.html. Full text in Research Archive

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  • Foote, Andrew David (2026). Museum collections provide a temporal record of past genetic variation. Proceedings of the National Academy of Sciences of the United States of America (PNAS). ISSN 0027-8424. 123(2). doi: 10.1073/pnas.2530586122. Full text in Research Archive
  • Taylor, Rebecca S.; Jensen, Evelyn L.; Coltman, David; Foote, Andrew & Lamichhaney, Sangeet (2021). Seeing the whole picture: What molecular ecology is gaining from whole genomes. Molecular Ecology. ISSN 0962-1083. 30, p. 5917–5922. doi: 10.1111/mec.16282. Full text in Research Archive
  • Taylor, Rebecca S.; Jensen, Evelyn L.; Coltman, David; Foote, Andrew & Lamichhaney, Sangeet (2021). Seeing the whole picture: What molecular ecology is gaining from whole genomes. Molecular Ecology. ISSN 0962-1083. 30(23), p. 5917–5922. doi: 10.1111/mec.16282. Full text in Research Archive

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Published Aug. 17, 2026 1:00 PM - Last modified Oct. 30, 2026 9:43 AM